α1A-selective adrenergic antagonist
Tamsulosin hydrochloride
Brand names: Flomax, Flomaxtra
Adult dose
Dose: 400 micrograms PO OD
Route: PO
Frequency: OD
Clinical pearls
- BPH symptom relief, ureteric stone expulsion
- Inform ophthalmologist before cataract surgery (IFIS)
Contraindications
- History of postural hypotension
- Severe hepatic impairment
- Hypersensitivity
Side effects
- Dizziness
- Postural hypotension
- Retrograde ejaculation
- IFIS (intra-op floppy iris)
- Headache
- Rhinitis
Interactions
- Other α-blockers
- Strong CYP3A4 modulators
- PDE5 inhibitors (additive hypotension)
Reference: BNF; NICE CG97; https://bnf.nice.org.uk/drugs/tamsulosin-hydrochloride/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.