OrthopaedicsNeurology
Lumbar Disc / Sciatica
Recognise red flags (cauda equina), conservative + analgesia + physio, MRI for refractory, surgery for severe.
Source: NICE NG59
Step 1 of ~3
info
Recognise + Red Flags
Sciatica: lumbar radiculopathy from disc prolapse / spinal stenosis; pain radiating down leg in dermatomal distribution + numbness / weakness.
Red flags requiring urgent investigation:
• Cauda equina syndrome: bilateral leg pain / weakness, saddle anaesthesia, urinary retention / incontinence, faecal incontinence, reduced anal tone — IMMEDIATE MRI + neurosurgical referral.
• Spinal cord compression: UMN signs.
• Cancer / infection: weight loss, night pain, fever, IV drug use, immunocompromise, recent infection.
• Trauma.
Examination: gait, straight leg raise (positive 30–70° = nerve root irritation L4-S1), femoral stretch test (L2-L4), neurology including dermatomes + reflexes + power.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Ranolazine · Refractory Stable Angina
- Protamine Sulphate (Heparin Reversal) · Heparin Reversal / Cardiac Surgery
- Tezepelumab (CRSwNP / Severe Asthma) · Anti-TSLP (Thymic Stromal Lymphopoietin) Monoclonal Antibody
- Quinine · Antimalarial — Severe / Complicated Malaria (IV) / Nocturnal Cramps (Oral)
- Paracetamol · Analgesia
- Ibuprofen · NSAID Analgesia
Pathways
- Hip Fracture Pathway · NICE CG124; BPT
- Cauda Equina Syndrome · Society of British Neurological Surgeons; BOA — Best Practice
- Knee Soft Tissue Injury (ACL / MCL / Meniscus) · BOA; Royal College of Surgeons
- Shoulder Dislocation · BOA; RCEM
- Scaphoid Fracture · BOA; BSSH
- Pelvic Fracture · BOA; ATLS; NICE NG39
Decision support only. Always apply local guidelines and clinical judgement.