Renal Drug Dosing
Dose adjustment in renal impairment — by eGFR, for any combination of medicines.
Add a patient's medicines to read the renal-impairment guidance from each drug's re-sourced product information. Wording that mentions avoiding the drug or changing the dose is listed first; "not documented" means the record has no renal guidance, not that no adjustment is needed. Enter an eGFR to see the CKD stage to read each drug's bands against. Use it alongside the eGFR calculator and the renal calculators.
Add the patient's medicines to see each one's renal guidance — wording that mentions avoiding the drug or changing the dose is listed first. Read each against the patient's eGFR yourself.
Renal wording comes from each drug's source labelling (UK SmPC, or the US label where noted) and has been clinician-reviewed. "Not documented" means the record has no renal guidance — not that no adjustment is needed. Confirm against the current SmPC.
Important
Decision support only. The renal wording comes from each drug's labelling and has been clinician-reviewed; the tool does not judge the patient's dose and is not exhaustive. Always confirm against the current SmPC or local renal guidance, and apply clinical judgement (including the choice of eGFR vs creatinine clearance) before prescribing.