Anaesthesia / ICU A

Multiple Organ Dysfunction Score (MODS)

Quantifies the degree of dysfunction in 6 organ systems: respiratory, renal, hepatic, cardiovascular, haematological, and neurological. Predicts ICU mortality. Complements SOFA score.

Score interpretation

Minimal Organ Dysfunction 0–4

MODS 0-4. Minimal organ dysfunction. Predicted mortality < 5%.

→ Standard ICU care. Monitor for deterioration. Treat underlying cause.

Moderate Organ Dysfunction 5–8

MODS 5-8. Moderate dysfunction. Predicted mortality 10-25%.

→ Goal-directed therapy. Optimise organ support. Daily reassessment. MDT approach.

Severe Organ Dysfunction 9–12

MODS 9-12. Severe dysfunction. Predicted mortality 25-50%.

→ Maximal organ support. ICU senior review. Prognosis discussion with family. Consider CRRT, vasopressors, mechanical ventilation as indicated.

Critical Organ Failure 13–24

MODS >= 13. Critical multi-organ failure. Predicted mortality > 50-75%.

→ Critical care escalation. Family meeting regarding prognosis. Treatment withdrawal assessment if clinically appropriate. Palliative care input if appropriate.

Interpretation bands for the MODS. Apply clinical judgement and local guidance.

References

Marshall JC, et al. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med. 1995;23(10):1638-1652.

Curated clinical cross-links plus same-class fallbacks.

Drugs

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.

Score interpretation

References

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