Manning Criteria for Irritable Bowel Syndrome
Clinical criteria for the diagnosis of IBS based on symptom pattern. The original IBS diagnostic criteria, predating Rome. ≥3 of 6 criteria suggests IBS.
Score interpretation
Fewer than 3 Manning criteria — IBS diagnosis unlikely
→ Investigate other causes of symptoms; consider coeliac, IBD, colorectal cancer screening if alarm features
≥3 Manning criteria — diagnosis consistent with IBS (75% sensitivity, 78% specificity)
→ Diagnose IBS if no alarm features (rectal bleeding, weight loss, age >50 with new symptoms, nocturnal symptoms); initiate IBS management
Interpretation bands for the Manning Criteria. Apply clinical judgement and local guidance.
References
- Manning AP et al. Towards positive diagnosis of the irritable bowel. BMJ. 1978;2(6138):653–654.
Related
Curated clinical cross-links plus same-class fallbacks.
- Kruis Score for Diagnosis of Irritable Bowel Syndrome · Functional GI Disorders
- Rome IV Diagnostic Criteria for Functional Dyspepsia · Functional GI Disorders
- Rome IV Diagnostic Criteria for Functional Constipation · Functional GI Disorders
- Rome IV Diagnostic Criteria for Functional Chest Pain · Functional GI Disorders
- Rome IV Diagnostic Criteria for Globus · Functional GI Disorders
- Rome IV Diagnostic Criteria for Cyclic Vomiting Syndrome (CVS) · Functional GI Disorders
- Aciclovir 800mg Tablets (Ramsay Hunt Syndrome / Herpes Zoster Oticus) · Antiviral — nucleoside analogue (herpes zoster treatment)
- Pramipexole (Restless Legs Syndrome — Elderly) · Dopamine Agonist (D2/D3 Receptor)
- Sodium Picosulfate · Stimulant Laxative / Bowel Preparation Agent
- Citric acid · Bowel preparation component
- Citric acid with magnesium carbonate · Osmotic bowel cleanser
- Macrogol 3350 with sulfate, ascorbate, KCl & NaCl (bowel prep) · Osmotic bowel cleanser
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.