Manning Criteria for Irritable Bowel Syndrome
Clinical criteria to support diagnosis of Irritable Bowel Syndrome (IBS). Positive predictive value increases with the number of criteria met. Predates Rome criteria.
Score interpretation
→ Manning 3–6 criteria: IBS is likely. Rule out organic pathology (FBC, CRP, coeliac screen, stool calprotectin, TSH). No alarm features (age >50, weight loss, PR bleeding, family history CRC) — consider flexible sigmoidoscopy. Positive diagnosis: gut-directed CBT, low-FODMAP diet, antispasmodics.
→ Manning <3 criteria: IBS less likely. Investigate for alternative diagnoses. If organic pathology excluded and clinical suspicion remains, apply Rome IV criteria.
Interpretation bands for the Manning Criteria (IBS). Apply clinical judgement and local guidance.
References
Related
Curated clinical cross-links plus same-class fallbacks.
- Methoxyflurane · Inhaled Analgesic — Acute Pain
- Aciclovir 800mg Tablets (Ramsay Hunt Syndrome / Herpes Zoster Oticus) · Antiviral — nucleoside analogue (herpes zoster treatment)
- Fentanyl Transdermal Patch (Elderly Chronic Pain) · Opioid Analgesic — Transdermal Patch
- Pramipexole (Restless Legs Syndrome — Elderly) · Dopamine Agonist (D2/D3 Receptor)
- Morphine Slow-Release (Elderly Chronic Pain) · Opioid Analgesic — Modified-Release Oral
- Sodium Picosulfate · Stimulant Laxative / Bowel Preparation Agent
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.