haematology dermatology
ABCDE Criteria for Melanoma Recognition
Five-feature clinical screening checklist for early melanoma recognition. Developed by Friedman et al. 1985. Expanded to include E (evolution). Primary care and emergency tool for urgent 2-week-wait referral decisions. Three or more features = suspicious; urgent dermatology referral indicated. Does not replace dermoscopy or biopsy.
References
- Friedman RJ et al. Early detection of malignant melanoma: the role of physician examination and self-examination of the skin. CA Cancer J Clin. 1985;35(3):130-151.
- NICE NG12. Suspected cancer: recognition and referral. NICE. 2015 (updated 2023). Melanoma section.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Chlorhexidine gluconate with isopropyl alcohol · Skin antiseptic
- Chlorhexidine with cetrimide · Skin antiseptic / wound cleanser
- Barrier creams and ointments · Topical skin protectant
- Risedronate Sodium · Bisphosphonate
- Zoledronic Acid · Bisphosphonate (IV)
- Denosumab · RANK Ligand Inhibitor (Anti-resorptive)
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Splenomegaly Workup · BSH; BMJ Best Practice
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.