Therapeutic Hypothermia Criteria (Neonatal HIE)
Identifies neonates with hypoxic ischaemic encephalopathy (HIE) eligible for therapeutic hypothermia (cooling therapy). TOBY/NICE criteria.
Score interpretation
Not all TOBY/BAPM entry criteria are met.
→ Supportive care; if a perinatal hypoxia criterion is met but the examination is normal, re-examine several times in the first 6 hours (BAPM); discuss borderline cases with the cooling centre.
Meets TOBY/BAPM criteria for therapeutic hypothermia.
→ Discuss with a consultant and the network NICU now; start therapeutic hypothermia (33–34 °C for 72 h) with continuous rectal temperature monitoring within 6 hours of birth; aEEG monitoring.
Interpretation bands for the Neonatal Cooling Criteria. Apply clinical judgement and local guidance.
References
Related
Curated clinical cross-links plus same-class fallbacks.
- Thiamine (IV/IM — Pabrinex) · Vitamin B1 (Thiamine) — deficiency treatment / Wernicke's encephalopathy prevention
- Aspirin (Loading Dose) · Antiplatelet — ACS / Ischaemic Stroke
- Alteplase (tPA) · Thrombolytic — Ischaemic Stroke / Massive PE
- Lactulose · Osmotic laxative / Ammonia reduction (hepatic encephalopathy)
- Lactulose (Hepatic Encephalopathy) · Osmotic Laxative / Ammonia-Reducing Agent
- Rozanolixizumab · Neonatal Fc receptor (FcRn) antagonist
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.
