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neonatology infectious-disease

Neonatal Early-Onset Sepsis (EOS) Calculator

Estimates risk of early-onset neonatal sepsis (EOS) using maternal and clinical factors. Based on Kaiser Permanente model.

Score interpretation

Low EOS risk

→ Routine care; clinical monitoring for 24-48h; no antibiotics required if well

Intermediate EOS risk

→ Blood culture; consider CBC and CRP at 4-6h; antibiotic decision based on clinical evolution; neonatology review

High EOS risk

→ Blood culture and LP if feasible; start empirical antibiotics (penicillin + gentamicin); NICU admission; close monitoring

Interpretation bands for the Neonatal EOS Risk. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.