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neurology

Hoehn & Yahr Staging for Parkinson's Disease

Original 1967 (and modified) staging of Parkinson's disease severity by motor symptoms and disability. Drives clinical decisions on therapy intensity and rehabilitation.

Score interpretation

Early disease (Stage 1–2) 1–2

→ Begin dopaminergic therapy when functionally indicated (levodopa first-line per NICE NG71). MDS-UPDRS to track. Annual driving assessment if motor signs prominent. Exercise (Tai Chi, dance) shown to slow progression.

Mid disease (Stage 2.5–3) 2.5–3

→ Optimise levodopa with adjuncts (MAO-B / COMT inhibitor, dopamine agonist). Specialist PD nurse, physiotherapy, OT. Falls prevention. Screen for non-motor symptoms (sleep, mood, autonomic, cognition).

Advanced disease (Stage 4) 4

→ Consider device-assisted therapy: deep brain stimulation, apomorphine infusion, levodopa-carbidopa intestinal gel (NICE TA681). Carer assessment. Advance care planning.

End-stage (Stage 5) 5

→ Multidisciplinary specialist PD service. Address dysphagia (SLT, gastrostomy), dementia (rivastigmine), end-of-life planning. Hospice / palliative-care input.

Interpretation bands for the Hoehn-Yahr. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.