Injury Severity Score (ISS)
Anatomical scoring of injury severity. Sum of squares of top 3 AIS scores from 6 body regions. Score >15 = major trauma.
Score interpretation
ISS 0–8: Minor injury. Low mortality.
→ Standard management based on individual injuries.
ISS 9–15: Moderate injury. Increased risk of complications.
→ Inpatient admission. Serial observations. Trauma team review.
ISS 16–24: Serious injury. Major trauma threshold (>15). Significant mortality risk.
→ Major trauma centre if available. Trauma team activation. Early CT pan-scan. Damage control surgery principles.
ISS 25–74: Severe to critical injury. High mortality.
→ Major trauma centre mandatory. ICU. Damage control resuscitation. Haemostatic resuscitation (1:1:1 pRBC:FFP:Plt).
ISS 75: AIS 6 in any region = automatically unsurvivable.
→ Palliative / comfort care. Family notification.
Interpretation bands for the ISS. Apply clinical judgement and local guidance.
References
- Baker SP et al. The Injury Severity Score: a method for describing patients with multiple injuries. J Trauma. 1974.
Related
Curated clinical cross-links plus same-class fallbacks.
- Difficult Airway Algorithm (DAS) · DAS 2015; Royal College of Anaesthetists
- Major Haemorrhage Protocol · NICE NG24; UK MHP guidelines
- New-Onset Atrial Fibrillation · ESC 2020 AF Guidelines; NICE NG196
- Hypertensive Emergency · ESC/ESH 2018 Hypertension Guidelines; NICE NG136
- Bradycardia Management · Resuscitation Council UK ABCDE; ESC 2021 Pacing Guidelines
- Ventricular Tachycardia / Fibrillation · Resuscitation Council UK ACLS; ESC 2022 Ventricular Arrhythmia Guidelines
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.