Mangled Extremity Severity Score (MESS)
Predicts the need for amputation in patients with traumatic lower limb injury. Score ≥7 = amputation predictive (97% sensitivity for amputation indication). Assesses skeletal/soft tissue injury, limb ischaemia, shock, and age.
Score interpretation
MESS <7 — limb salvage likely feasible
→ Attempt limb salvage; orthopaedic/vascular surgery involvement; revascularisation if ischaemic; wound debridement and fixation; antibiotics for open fracture; ATLS protocol; reassess at 24–48h
MESS ≥7 — high predictive value for amputation requirement
→ Senior orthopaedic/vascular surgeon discussion; primary amputation may be appropriate; do NOT use MESS alone for amputation decision — clinical context, patient factors, and functional goals must be considered; document discussion with patient and family; trauma MDT; psychological support; prosthetics team early involvement
Interpretation bands for the MESS Score. Apply clinical judgement and local guidance.
References
- Johansen K et al. Objective criteria accurately predict amputation following lower extremity trauma. J Trauma. 1990;30(5):568–572.
Related
Curated clinical cross-links plus same-class fallbacks.
- Tranexamic Acid (ICU/Trauma/Surgical) · Antifibrinolytic
- Sofosbuvir with velpatasvir and voxilaprevir · Pan-genotypic DAA salvage combination
- Bevacizumab (Intravitreal) · Anti-VEGF (Vascular Endothelial Growth Factor Inhibitor)
- Posaconazole · Antifungal — Aspergillosis Prophylaxis / Salvage
- Tranexamic Acid (Surgical / Trauma Haemorrhage) · Antifibrinolytic (Haemostatic)
- Enoxaparin (Vascular) · Low Molecular Weight Heparin
- Hip Fracture Management · NICE CG124 / BOA 2020
- Distal Radius Fracture · BOA / NICE
- Ankle Fracture Management · BOA / Lauge-Hansen classification
- Metastatic Spinal Cord Compression · NICE CG75 2020
- Open Fracture Management · BOA/BAPRAS 2017
- OrthoPath: Upper Limb ED Triage · OrthoPath ED Tool — ReviseMRCEM.com
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.