FRAX Score (Fracture Risk Assessment)
Estimates 10-year probability of hip and major osteoporotic fracture. Guides DEXA scan referral and bisphosphonate initiation per NOGG/NICE guidelines.
Score interpretation
→ Lifestyle advice: calcium 700-1200mg/day dietary, vitamin D 800-1000 IU/day; weight-bearing exercise; fall prevention; reassess in 5 years
→ DEXA scan; if T-score <=-2.5 (osteoporosis) or <=-1.0 with multiple risk factors: bisphosphonate (alendronate 70mg weekly first-line); calcium and vitamin D supplementation; NOGG threshold calculator
→ Bisphosphonate without awaiting DEXA if >75 and low-energy fracture; alendronate 70mg weekly; risedronate or zoledronate (annual IV) if GI intolerance; denosumab 60mg SC 6-monthly for severe osteoporosis; post-fracture liaison service referral
Interpretation bands for the FRAX Score. Apply clinical judgement and local guidance.
References
Related
Curated clinical cross-links plus same-class fallbacks.
- Alendronic Acid (Alendronate) · Bisphosphonate (bone resorption inhibitor)
- Zoledronic Acid · IV Bisphosphonate
- Zoledronic Acid · Bisphosphonate
- Denosumab · Anti-RANKL Monoclonal Antibody
- Ibandronate · Bisphosphonate (Osteoporosis)
- Pamidronate Disodium · IV Bisphosphonate (Paget's Disease / Bone Metastases / Hypercalcaemia)
- Hip Fracture Management · NICE CG124 / BOA 2020
- Distal Radius Fracture · BOA / NICE
- Ankle Fracture Management · BOA / Lauge-Hansen classification
- Metastatic Spinal Cord Compression · NICE CG75 2020
- Open Fracture Management · BOA/BAPRAS 2017
- OrthoPath: Upper Limb ED Triage · OrthoPath ED Tool — ReviseMRCEM.com
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.