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paediatrics rheumatology cardiology

Kawasaki Disease Diagnostic Criteria

Diagnoses Kawasaki disease using AHA/JCS classic and incomplete criteria. Guides IVIG and aspirin therapy to prevent coronary artery aneurysms.

Score interpretation

Classic Kawasaki Disease (with fever) 4–5

Fever ≥ 5 days with ≥ 4 principal features (AHA 2017).

→ Treat as Kawasaki disease: urgent paediatric review; IVIG and aspirin per the local paediatric protocol and a children's formulary; echocardiogram at diagnosis.

Incomplete Kawasaki Disease — Assess Further 2–3

Fever ≥ 5 days with 2–3 principal features.

→ Measure CRP and ESR; if CRP ≥ 30 mg/L or ESR ≥ 40 mm/h apply the AHA 2017 supplementary laboratory criteria and echocardiography; paediatric cardiology / infectious disease review.

KD Criteria Not Met 0–1

No fever ≥ 5 days, or fewer than 2 principal features.

→ Fever ≥ 5 days is required; experienced clinicians may diagnose KD after 4 days of fever when ≥ 4 principal features are present, and infants with ≥ 7 days of unexplained fever need evaluation for incomplete KD. Consider alternative diagnoses (viral exanthem, scarlet fever, adenovirus, drug reaction, systemic JIA).

Interpretation bands for the Kawasaki Disease. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.