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Respiratory General Medicine Strong — GOLD 2023 / NICE NG115

GOLD COPD Classification

GOLD 2023 ABE assessment: groups COPD by exacerbation history and symptom burden (CAT/mMRC) to guide initial therapy. The spirometric grade (GOLD 1–4) and blood eosinophil count are recorded alongside; they do not change the group.

Used in: COPD

CAT ≥ 10 OR mMRC ≥ 2 = high symptom burden

Guides inhaled corticosteroid (ICS) addition

Score interpretation

GOLD Group A — Low Risk, Low Symptoms 1

GOLD Group A: 0–1 moderate exacerbations (none leading to hospital admission) and low symptom burden (mMRC 0–1, CAT < 10).

→ Initial therapy: SABA or SAMA PRN. If symptoms persist: LAMA or LABA. Annual spirometry. Smoking cessation. Pulmonary rehabilitation if deconditioning.

GOLD Group B — Low Risk, High Symptoms 2

GOLD Group B: 0–1 moderate exacerbations (none leading to hospital admission) and high symptom burden (mMRC ≥ 2 or CAT ≥ 10).

→ Initial therapy: LAMA + LABA dual bronchodilator. Pulmonary rehabilitation. Annual influenza + pneumococcal vaccination.

GOLD Group E — High Exacerbation Risk 3

GOLD Group E (formerly C/D): ≥ 2 moderate exacerbations or ≥ 1 leading to hospitalisation in the past year. Significant morbidity and mortality risk.

→ Initial therapy: LAMA + LABA; consider LAMA + LABA + ICS if blood eosinophils ≥ 300 cells/µL. Pulmonary rehabilitation. Assess for long-term oxygen therapy (LTOT) if SpO₂ ≤ 88% at rest.

Interpretation bands for the GOLD COPD. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.