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Respiratory General Medicine Strong — GOLD 2023 / NICE NG115

GOLD COPD Classification

GOLD 2023 ABCD assessment tool for COPD combining symptom burden (CAT/mMRC) and exacerbation history to guide therapy.

Used in: COPD

CAT ≥ 10 OR mMRC ≥ 2 = high symptom burden

Guides inhaled corticosteroid (ICS) addition

Score interpretation

GOLD Group A — Low Risk, Low Symptoms 1–2

GOLD Group A: Low exacerbation risk, low symptom burden, mild-moderate airflow limitation.

→ Initial therapy: SABA or SAMA PRN. If symptoms persist: LAMA or LABA. Annual spirometry. Smoking cessation. Pulmonary rehabilitation if deconditioning.

GOLD Group B — Low Risk, High Symptoms 3–4

GOLD Group B: Low exacerbation risk, high symptom burden.

→ Initial therapy: LAMA + LABA dual bronchodilator. Pulmonary rehabilitation. Annual influenza + pneumococcal vaccination. Consider ICS if eosinophils ≥ 300.

GOLD Group E — High Exacerbation Risk 5–99

GOLD Group E (formerly C/D): High exacerbation risk. Significant morbidity and mortality risk.

→ Initial therapy: LAMA + LABA. Add ICS if eosinophils ≥ 100 + ≥1 exacerbation. Consider roflumilast (FEV₁ < 50%, chronic bronchitis phenotype). Pulmonary rehabilitation. Assess for long-term oxygen therapy (LTOT) if SpO₂ ≤ 88% at rest.

Interpretation bands for the GOLD COPD. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.