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Amide LA + vasoconstrictor

Mepivacaine with adrenaline

Brand names: Scandonest with adrenaline

Adult dose

Dose: Per procedure (dental); max 4.4 mg/kg
Route: Infiltration / nerve block
Frequency: per procedure

Clinical pearls

  • Dental anaesthesia with vasoconstriction

Contraindications

  • As mepivacaine
  • Severe hypertension
  • Tachyarrhythmia
  • Concurrent MAOI

Side effects

  • Tachycardia
  • Hypertension
  • LA toxicity

Interactions

  • MAOIs
  • TCAs
  • β-blockers

Reference: BNF; https://bnf.nice.org.uk/drugs/mepivacaine-with-adrenaline/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.