Loop diuretic

Torasemide

Brand names: Torem

Torasemide is a loop diuretic used for oedema associated with heart failure, renal or hepatic disease, and for hypertension.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

It inhibits the sodium-potassium-chloride co-transporter in the thick ascending limb of the loop of Henle, promoting natriuresis and diuresis.

Prescribing in practice

It can cause electrolyte disturbance, including hypokalaemia and hyponatraemia, and volume depletion with associated renal impairment.
Use with caution in patients with gout, as it can raise serum urate.
Caution with other ototoxic or nephrotoxic drugs and avoid combinations that increase the risk of electrolyte imbalance.

Monitoring

Monitor electrolytes, renal function, fluid status and blood pressure during treatment.

Counselling the patient

It increases urine output; taking it earlier in the day can avoid disturbed sleep.
Report muscle cramps, marked weakness, dizziness or palpitations.
Attend for blood tests to check kidney function and salts.

Evidence & guidelines

Loop diuretics are a mainstay of symptomatic relief in fluid overload and heart failure, consistent with NICE guidance.

Reference: ESC HF; Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Curated clinical cross-links plus same-class fallbacks.

Drugs

Pathways