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Loop diuretic

Torasemide

Brand names: Torem

Adult dose

Dose: HF: 5–20mg PO OD (max 40mg/day). HTN: 2.5–5mg OD
Route: PO/IV
Frequency: OD

Clinical pearls

  • HFrEF (TRANSFORM-HF — non-inferior to furosemide); HTN; oedema
  • Equivalent dose: torasemide 10mg ≈ furosemide 40mg

Contraindications

  • Anuria
  • Severe hypotension
  • Severe hepatic impairment
  • Hypersensitivity to sulfonamides
  • Hypovolaemia

Side effects

  • Hypokalaemia
  • Hyponatraemia
  • Dehydration
  • Hyperuricaemia
  • Renal impairment
  • Ototoxicity (less than furosemide)

Interactions

  • NSAIDs
  • Lithium
  • Aminoglycosides
  • Digoxin (if hypokalaemia)

Monitoring

  • U&E
  • Weight
  • BP

Reference: BNF; ESC HF; https://bnf.nice.org.uk/drugs/torasemide/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.