Camellia sinensis (sinecatechins)

How it works

The catechins, predominantly epigallocatechin gallate, have antioxidant and immunomodulatory properties, although the precise mechanism in clearing genital warts is not fully established.

Prescribing in practice

• Local skin and mucosal reactions such as erythema, itching, burning and pain are very common and expected as part of treatment.
• It should not be applied to open wounds, and the treated area should not be covered with occlusive dressings.
• It may weaken latex condoms and diaphragms, so advise on alternative contraception during use.

Monitoring

Review the treated area periodically for response and to assess the severity of local reactions.

Counselling the patient

• Apply a thin layer to each wart and do not wash off before the next planned application.
• Local redness, itching and discomfort are common and usually tolerable.
• Avoid relying on condoms or diaphragms for protection while using this ointment.

Evidence & guidelines

Sinecatechins ointment is licensed for the treatment of external anogenital warts based on its clinical trial evidence.