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Topical emollient (paraffin base)

Emollient creams and ointments, paraffin-containing

Brand names: Diprobase, Cetraben, Doublebase, Epaderm, Hydromol, Zerobase

Paraffin-containing emollient creams and ointments are leave-on moisturisers used to manage dry, scaling and eczematous skin conditions.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

They act as occlusive and humectant barriers that reduce transepidermal water loss, soften the stratum corneum and help restore skin barrier function.

Prescribing in practice

  • Paraffin-based emollients are a fire hazard: dressings, clothing and bedding contaminated with the product can ignite readily near naked flames or cigarettes, so patients must avoid smoking and open flames.
  • Apply liberally and frequently, smoothing in the direction of hair growth to reduce the risk of folliculitis.
  • Decant from tubs with a clean spoon or pump rather than fingers to minimise bacterial contamination.

Monitoring

No laboratory monitoring is required; review adequacy of skin hydration, product acceptability and any local reactions.

Counselling the patient

  • Keep away from naked flames and do not smoke; fabrics soaked with the emollient can catch fire even after washing.
  • Apply generously and often, especially after washing while the skin is still damp.
  • Use a clean spoon or pump to remove product from tubs to keep it hygienic.

Evidence & guidelines

The MHRA has issued safety advice on the fire risk of paraffin-based and paraffin-free emollients, and NICE guidance positions emollients as first-line in dry skin and eczema.

Reference: NICE NG198; NICE CKS Eczema; BAD; MHRA Drug Safety Update; Confirm identity and dosing against the manufacturer SPC (eMC) and NICE. Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.