Potent topical corticosteroid
Hydrocortisone butyrate
Brand names: Locoid
Adult dose
Dose: Apply thinly OD–BD
Route: Topical
Frequency: OD-BD
Clinical pearls
- Note: despite the name, this is potent — different from plain hydrocortisone (mild)
- Eczema, psoriasis
Contraindications
- Untreated infection
- Rosacea
- Acne
- Perioral dermatitis
Side effects
- Skin atrophy
- Striae
- Telangiectasia
- Local irritation
Reference: BNF; NICE CG57; https://bnf.nice.org.uk/drugs/hydrocortisone-butyrate/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Drugs
Pathways
- Suspicious Pigmented Lesion — Melanoma Pathway · NICE NG14 2015 / BAD
- Cellulitis and Erysipelas · NICE NG141 2019 / CREST
- Psoriasis — Severity Assessment and Step-Up Therapy · NICE NG153 2019 / BAD
- Atopic Eczema — Assessment and Step-Up Therapy · NICE NG95 2023
- Urticaria and Angioedema · BSACI / EAACI Guidelines 2022
- Acne Vulgaris — Grading and Treatment · NICE NG198 2021 / BAD