Potent topical corticosteroid

Fluocinonide

Brand names: Metosyn

Fluocinonide is a potent topical corticosteroid used for steroid-responsive inflammatory dermatoses such as eczema and psoriasis.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

It binds glucocorticoid receptors in skin cells to produce anti-inflammatory, immunosuppressive and vasoconstrictive effects.

Prescribing in practice

Because it is potent, prolonged use, large surface areas, occlusion, or use on the face and flexures increases the risk of skin atrophy and systemic absorption; use the lowest effective potency for the shortest time.
Reserve potent steroids for thicker or more resistant lesions and step down as the condition improves.
Avoid application to untreated infected skin.

Monitoring

No routine laboratory monitoring is required; review for treatment response and signs of local steroid-induced skin changes.

Counselling the patient

Apply a thin layer to affected skin only and avoid the face unless specifically advised.
Do not use on infected or broken skin without medical advice.
Keep using emollients alongside the steroid.

Evidence & guidelines

Potent topical corticosteroids are an established option for resistant inflammatory dermatoses, consistent with NICE potency-matched prescribing.

Reference: Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Curated clinical cross-links plus same-class fallbacks.

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