Antidote / sclerosant
Alcohol (ethanol)
Brand names: Ethanol injection
Adult dose
Dose: Ethylene glycol/methanol toxicity: loading 0.6 g/kg then maintenance per TOXBASE (where fomepizole unavailable)
Route: Oral/IV
Frequency: Per regimen
Clinical pearls
- Fomepizole preferred where available; aim ethanol 100–150 mg/dL
- Also used as sclerosant in interventional radiology
Contraindications
- Pregnancy (relative)
- Hepatic failure
Side effects
- Sedation
- Hypoglycaemia (children)
- Lactic acidosis
Interactions
- CNS depressants
- Disulfiram
- Metronidazole
Monitoring
- Glucose, U&E
- Ethanol level
Reference: BNF; TOXBASE/NPIS; AACT position paper. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Pathways
- Paracetamol overdose · TOXBASE/NPIS; MHRA DSU 2012/2024; SNAP regimen (Lancet 2014); BNF
- TCA overdose · TOXBASE/NPIS; AACT/EAPCCT position statements; Resuscitation Council UK ALS
- Opioid overdose · TOXBASE/NPIS; Resuscitation Council UK; BNF
- Anticholinergic toxidrome · TOXBASE/NPIS; AACT/EAPCCT; BNF
- Benzodiazepine overdose · TOXBASE/NPIS; AACT/EAPCCT; BNF
- β-blocker overdose · TOXBASE/NPIS; AACT/EAPCCT; ESC; BNF