Topical counter-irritant

Levomenthol

Brand names: Aramint, Dermacool

Levomenthol (the levorotatory isomer of menthol) is a topical counter-irritant and cooling agent used to relieve pruritus and minor musculoskeletal aches, and is included in some inhalations.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

It activates cold-sensitive TRPM8 receptors producing a cooling sensation that can mask itch and pain, and provides a mild local analgesic and decongestant-type effect.

Prescribing in practice

Avoid contact with the eyes, broken or inflamed skin and mucous membranes, and do not apply to areas of skin breakdown.
Menthol-containing inhalations and nasal products should be used cautiously in infants and young children, in whom strong aromatic preparations can be hazardous.
Localised skin irritation or hypersensitivity can occur, prompting discontinuation.

Monitoring

Monitor the treated skin for adequate symptom relief and for any irritation or allergic reaction.

Counselling the patient

Apply to intact skin only and wash your hands after use, avoiding the eyes.
Stop using it if the skin becomes irritated or a rash develops.

Evidence & guidelines

The cooling and antipruritic effects of topical menthol are well established in dermatological practice and product information.

Reference: Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Curated clinical cross-links plus same-class fallbacks.

Pathways