Vaccine
Hepatitis B vaccine
Brand names: Engerix B, HBvaxPro, Fendrix
Adult dose
Dose: 3 doses at 0, 1, 6 months. Accelerated: 0, 1, 2 months + 12-month booster. Rapid (Engerix B): 0, 7, 21 days + 12-month booster
Route: IM
Frequency: course
Clinical pearls
- Healthcare workers, dialysis patients, IVDU, MSM, partners of HBsAg+ individuals, travellers, infants in childhood programme
- Check anti-HBs ≥10 mIU/mL post-vaccination in healthcare workers
Contraindications
- Severe hypersensitivity to previous dose or yeast
Side effects
- Local reaction
- Fatigue
- Headache
- Myalgia
Reference: BNF; UK Green Book; https://bnf.nice.org.uk/drugs/hepatitis-b-vaccine/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- Maddrey Discriminant Function (Alcoholic Hepatitis) · Alcoholic Liver Disease
- Lille Model (Steroid Response in Alcoholic Hepatitis) · Alcoholic Liver Disease
- FIB-4 Index · Liver Fibrosis
- Maddrey's Discriminant Function for Alcoholic Hepatitis · Hepatology
- Lille Model for Alcoholic Hepatitis · Hepatology
- AST to Platelet Ratio Index (APRI) · Hepatology
Drugs
Pathways
- Infective Endocarditis · ESC 2023 Infective Endocarditis Guidelines; NICE NG41
- Eczema Herpeticum · BAD; NICE CKS
- Suspected Bacterial Meningitis (Adult) · NICE NG240 (2024); NICE NG143 (paeds)
- Clostridioides difficile Colitis · NICE NG199 (2021); IDSA/SHEA 2021
- Returning Traveller — Fever · NaTHNaC; PHE; ESCMID 2018
- Malaria — Diagnosis & Management · PHE 2016; WHO 2023