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Vaccine

Cholera vaccine (live attenuated, oral)

Brand names: Vaxchora

Adult dose

Dose: Single oral dose ≥10 days before potential exposure
Route: PO
Frequency: once

Clinical pearls

  • Live attenuated CVD 103-HgR strain; rapid protection (~10 days)

Contraindications

  • Immunosuppression
  • Pregnancy unless benefit > risk

Side effects

  • Tiredness
  • Headache
  • Abdominal pain

Interactions

  • Avoid antibiotics 14 days before to 10 days after
  • Hypochlorhydria reduces efficacy

Reference: BNF; UK Green Book; https://bnf.nice.org.uk/drugs/cholera-vaccine-live/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.