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Bioflavonoid (rutin)

Oxerutins

Brand names: Paroven

Oxerutins are a group of hydroxyethylrutosides used to relieve symptoms of chronic venous insufficiency, such as oedema, aching and heaviness of the legs.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

They are thought to reduce capillary permeability and improve venous tone, helping to limit oedema.

Prescribing in practice

  • These agents relieve symptoms only and are an adjunct to, not a replacement for, compression therapy and other management of venous disease.
  • They do not treat the underlying venous pathology and benefit may be modest.
  • Use with caution in pregnancy, generally avoiding use in the first trimester.

Monitoring

Monitor symptomatic response and continue only if there is clear benefit.

Counselling the patient

  • This treatment helps symptoms but does not cure the underlying vein problem.
  • Continue to wear compression hosiery if it has been recommended.
  • Elevate the legs when resting to help reduce swelling.

Evidence & guidelines

Evidence for oxerutins is limited to symptomatic relief in chronic venous insufficiency, with compression remaining the mainstay of treatment.

Reference: Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.