Vascular SurgeryEndocrinology
Diabetic Foot — Vascular Component
Vascular component of diabetic foot disease; assess perfusion (ABPI / TBPI / TcPO₂); revascularisation for ischaemic ulcer / limb-threatening.
Source: NICE NG19; IWGDF
Step 1 of ~2
info
Recognise + Assessment
Diabetic foot disease combines:
• Peripheral neuropathy (most common) — loss of sensation, motor, autonomic.
• Peripheral arterial disease (PAD) — ischaemia.
• Infection.
Vascular assessment essential in all diabetic foot disease + ulceration.
• Examination: pedal pulses (DP, PT), capillary refill, skin colour, temperature, hair loss, ulcer location (neuropathic — pressure points; ischaemic — toes, heels, lateral foot).
• Ankle-brachial pressure index (ABPI): often falsely elevated in diabetes (medial arterial calcification — 'pipe stem' arteries) — TBPI more reliable.
• Toe brachial pressure index (TBPI): <0.7 abnormal.
• Transcutaneous oxygen tension (TcPO₂): <30 mmHg significant ischaemia.
• Doppler USS waveforms.
• Refer to multidisciplinary foot team within 24h (NICE NG19).
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Amlodipine · Dihydropyridine Calcium Channel Blocker — Raynaud's / Peripheral Vascular Disease / Hypertension
- Nicorandil · Potassium channel activator with nitrate component
- Methotrexate (Dermatology — Psoriasis) · Disease-Modifying Antirheumatic / Immunosuppressant
- Aspirin (Loading Dose) · Antiplatelet — ACS / Ischaemic Stroke
- Alteplase (tPA) · Thrombolytic — Ischaemic Stroke / Massive PE
- Acetazolamide (Ménière's Disease) · Carbonic Anhydrase Inhibitor (Diuretic)
Pathways
Decision support only. Always apply local guidelines and clinical judgement.