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Cardiology Emergency Medicine General Medicine Strong — ESC Guideline (2020)

HAS-BLED Score

Estimates 1-year risk of major bleeding in anticoagulated patients with AF.

Used in: Atrial Fibrillation

Systolic BP > 160 mmHg

Dialysis, transplant, or creatinine > 200 µmol/L

Cirrhosis, bilirubin >2×ULN, or AST/ALT/ALP >3×ULN

Unstable / high INR, time in therapeutic range < 60%

Antiplatelets, NSAIDs

How to use & interpret

HAS-BLED estimates 1-year risk of major bleeding in patients with atrial fibrillation being considered for, or taking, anticoagulation. Its main value is flagging and addressing modifiable bleeding risk factors (uncontrolled hypertension, labile INR, concurrent antiplatelets/NSAIDs, harmful alcohol use) — not to withhold anticoagulation.

A score ≥3 indicates higher bleeding risk warranting caution and closer review, but a high HAS-BLED on its own should rarely override a clear anticoagulation indication, because stroke risk usually outweighs bleeding risk. Use it alongside CHA₂DS₂-VASc, not instead of it.

Score interpretation

Low Bleeding Risk 0–2

Score 0–2: Low 1-year bleeding risk (~1–2%). Anticoagulation benefit likely outweighs risk.

→ Anticoagulation is appropriate. Address modifiable risk factors.

High Bleeding Risk 3–9

Score ≥3: High bleeding risk (~3.7–12.5%/year). Does NOT mean anticoagulation is contraindicated.

→ Correct modifiable risk factors. Clinical judgement required — weigh against stroke risk (CHA₂DS₂-VASc). Regular review.

Interpretation bands for the HAS-BLED. Apply clinical judgement and local guidance.

Frequently asked questions

Does a high HAS-BLED mean I should stop anticoagulation?

Usually no. It identifies and prompts correction of modifiable bleeding risks and flags patients needing closer monitoring. Stroke risk typically still favours anticoagulation.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.