General / Multi-Specialty A
Sensitivity / Specificity / PPV / NPV Calculator
Calculates sensitivity, specificity, PPV, and NPV from a 2x2 contingency table. Essential for evaluating diagnostic tests.
Score interpretation
Excellent Discrimination 90–100
Balanced accuracy ≥ 90 % — excellent discrimination.
→ Test highly reliable for ruling in or ruling out disease.
Good Discrimination 70–90
Balanced accuracy 70–90 % — good but imperfect discrimination.
→ Consider clinical context. PPV/NPV depend on disease prevalence.
Poor Discrimination 0–70
Balanced accuracy < 70 % — limited discrimination.
→ Use as adjunct only. Consider gold-standard confirmatory test.
Interpretation bands for the Sens/Spec. Apply clinical judgement and local guidance.
References
- Altman DG, Bland JM. Diagnostic tests 1: Sensitivity and specificity. BMJ. 1994;308(6943):1552.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Tetracosactide · Synthetic ACTH (short Synacthen test)
- Urea (13C) · 13C-urea breath test
- Fluorescein Sodium 2% Eye Drops · Diagnostic ophthalmic dye
- Indocyanine Green (Intravitreal Chromovitrectomy) · Diagnostic Dye — Vitreoretinal Surgery / ICG Angiography
- Fluorescein sodium · Ophthalmic diagnostic dye
- Fluorescein with lidocaine · Topical anaesthetic + diagnostic dye
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.