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gi-hepatology oncology

GALAD Model for HCC Diagnosis

GALAD biomarker model for early detection of hepatocellular carcinoma (HCC) in patients with cirrhosis or chronic hepatitis. Combines sex, age, AFP-L3, AFP, and DCP (PIVKA-II).

Score interpretation

GALAD below −0.63 — HCC Less Likely -99–-0.64

Below the conventional cut-off (about 90 % specificity).

→ Continue surveillance per guideline.

GALAD −0.63 or above — HCC More Likely -0.63–99

At or above the conventional cut-off.

→ Multiphase CT or MRI; hepatology / HCC MDT.

Interpretation bands for the GALAD Model. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.