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gi-hepatology surgery

Tokyo Guidelines 2018 — Acute Cholangitis Severity

Tokyo Guidelines 2018 (TG18) for grading severity of acute cholangitis to guide management decisions including timing of biliary drainage.

Score interpretation

Grade I — Mild 0–2

Grade I: acute cholangitis without Grade II/III features

→ IV antibiotics; biliary drainage semi-elective (within 24–48h); oral antibiotics after improvement

Grade II — Moderate 3–4

Grade II: not responsive to initial medical treatment or has specified features (high WBC, fever >39°C, age >75, bilirubin ≥85 μmol/L, hypoalbuminaemia)

→ Urgent biliary drainage (ERCP within 24h); IV broad-spectrum antibiotics; close monitoring

Grade III — Severe 5–10

Grade III: organ dysfunction present (cardiovascular, renal, respiratory, hepatic, haematological, neurological)

→ Emergency biliary drainage; ICU admission; aggressive resuscitation; multidisciplinary team involvement

Interpretation bands for the TG18 Cholangitis. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.