IE Prophylaxis Indication
Identifies patients requiring antibiotic prophylaxis before dental procedures based on ESC/AHA guidelines.
Score interpretation
No condition in the highest-risk group (ESC 2015).
→ Standard dental care without prophylaxis
Prophylaxis is not recommended for other dental or for non-dental procedures (ESC 2015).
→ No antibiotic prophylaxis for this procedure; reinforce oral and skin hygiene and regular dental review.
ESC 2015: antibiotic prophylaxis should be considered. In the UK, NICE CG64 does not recommend routine prophylaxis for dental procedures — discuss with the patient and their cardiologist.
→ Adults: amoxicillin 2g PO 30–60 min before procedure. Penicillin allergy: cephalexin (not after penicillin anaphylaxis, angioedema or urticaria), azithromycin, clarithromycin or doxycycline — clindamycin is no longer recommended (AHA 2021). Children: use a children's formulary.
Interpretation bands for the IE Prophylaxis. Apply clinical judgement and local guidance.
References
- Habib G, et al. 2015 ESC Guidelines for the management of infective endocarditis. Eur Heart J. 2015;36(44):3075-3128.
- Wilson WR, et al. Prevention of viridans group streptococcal infective endocarditis: a scientific statement from the American Heart Association. Circulation. 2021;143(20):e963–e978.
- NICE CG64. Prophylaxis against infective endocarditis. 2008 (updated 2016).
Related
Curated clinical cross-links plus same-class fallbacks.
- Atovaquone · Antiparasitic / Antifungal — PCP Prophylaxis / Treatment / Malaria
- Atovaquone with Proguanil Hydrochloride · Antimalarial (Combination — Prophylaxis and Treatment)
- Enoxaparin (VTE in Pregnancy) · Low Molecular Weight Heparin (LMWH) — VTE Prophylaxis/Treatment
- Low Molecular Weight Heparin (Pregnancy VTE) · Anticoagulant — VTE Treatment and Prophylaxis in Pregnancy
- Fondaparinux · Indirect Factor Xa Inhibitor — VTE Prophylaxis / Treatment
- Tinzaparin · Low Molecular Weight Heparin — VTE Treatment / Prophylaxis
- Infective Endocarditis · ESC 2023 Infective Endocarditis Guidelines; NICE NG41
- Eczema Herpeticum · BAD; NICE CKS
- Suspected Bacterial Meningitis (Adult) · NICE NG240 (2024); NICE NG143 (paeds)
- Clostridioides difficile Colitis · NICE NG199 (2021); IDSA/SHEA 2021
- Returning Traveller — Fever · NaTHNaC; PHE; ESCMID 2018
- Malaria — Diagnosis & Management · PHE 2016; WHO 2023
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.