infectious-disease critical-care emergency-medicine

SOFA Score (Sepsis-3)

Sequential Organ Failure Assessment (SOFA) score for organ dysfunction in ICU. Core of Sepsis-3 definition: sepsis = SOFA increase >=2.

Used in: Sepsis

Score interpretation

Minimal organ dysfunction

→ Routine monitoring; treat underlying infection

Moderate organ dysfunction

→ HDU/ICU level care; SOFA increase >=2 = sepsis; organ-specific support

Significant organ dysfunction

→ ICU; multiple organ support; consider septic shock if vasopressors needed and lactate >2

Severe multi-organ failure

→ High mortality; aggressive resuscitation; escalation plan; consider ECMO if appropriate

Interpretation bands for the SOFA Score. Apply clinical judgement and local guidance.

Curated clinical cross-links plus same-class fallbacks.

Calculators

Drugs

Pathways

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.