Anaesthesia & ICU Emergency Medicine General Medicine Strong — Sepsis-3 Consensus / NICE NG51
SIRS, Sepsis & Septic Shock Criteria
Systemic Inflammatory Response Syndrome (SIRS) criteria and Sepsis-3 definitions. SIRS ≥ 2 criteria; Sepsis = life-threatening organ dysfunction caused by dysregulated response to infection.
References
- Singer M et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016.
- NICE NG51. Sepsis: recognition, diagnosis and early management. 2016.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Drugs
- Hydrocortisone (ICU — Stress Dosing) · Corticosteroid (ICU/Septic Shock)
- Noradrenaline (Cardiogenic Shock / Vasopressor) · Vasopressor / Cardiogenic Shock
- Vasopressin / Terlipressin · Vasopressin Analogue — Vasodilatory Shock / Variceal Bleeding
- Ceftriaxone (Paediatric) · Third-Generation Cephalosporin — Meningitis / Sepsis / Community-Acquired Pneumonia
- Gentamicin (Paediatric) · Aminoglycoside — Neonatal Sepsis / Gram-Negative Infections in Children
- Flucloxacillin (Burns — Wound Infection) · Antibiotic — Penicillinase-Resistant Penicillin
Pathways
- Difficult Airway Algorithm (DAS) · DAS 2015; Royal College of Anaesthetists
- Anaphylaxis Under Anaesthesia · AAGBI 2018; NAP6
- Malignant Hyperthermia · AAGBI 2011; MHAUS
- Local Anaesthetic Systemic Toxicity (LAST) · AAGBI 2010; ASRA 2017
- Spinal Anaesthesia Hypotension Management · AAGBI; ASA
- Postoperative Nausea & Vomiting · Society for Ambulatory Anesthesia 2020; AAGBI
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.