neonatology
Neonatal Partial Exchange Transfusion for Polycythaemia
Calculates volume of blood to exchange with normal saline to reduce haematocrit in neonatal polycythaemia. Polycythaemia defined as venous Hct ≥65% (Hb ≥220 g/L). Treatment indicated if symptomatic or Hct ≥70%.
References
- Black VD, Lubchenco LO. Neonatal polycythemia and hyperviscosity. Pediatr Clin North Am. 1982;29(5):1137–1148.
- British Association of Perinatal Medicine. Guideline on polycythaemia and hyperviscosity in neonates. BAPM. 2011.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Celiprolol hydrochloride · Cardioselective beta-blocker (β1 + β2 partial agonist)
- Buprenorphine · Opioid partial agonist (μ-receptor partial agonist, κ-antagonist)
- Colestyramine (Cholestyramine) · Bile Acid Sequestrant / Ion Exchange Resin
- Rituximab (Haematology) · Anti-CD20 Monoclonal Antibody
- Rozanolixizumab · Neonatal Fc receptor (FcRn) antagonist
- Efgartigimod alfa · Neonatal Fc receptor (FcRn) blocker
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.