Rh(D) Immune Globulin Dosage for Maternal-Fetal Haemorrhage
Calculates appropriate dose of Rh(D) immune globulin (anti-D) after maternal-fetal haemorrhage in Rh(D)-negative women. Based on Kleihauer-Betke test result. Prevents Rh sensitisation.
Score interpretation
The standard 500 IU dose (adults) covers a FMH up to 4 mL fetal red cells (BSH). Children: use a children's formulary.
→ Give within 72 hours of the sensitising event.
Adults: 125 IU per mL fetal red cells IM (67.5 IU per mL if given IV) (BSH). Children: use a children's formulary.
→ Confirm the FMH by flow cytometry; discuss with the transfusion laboratory; follow-up FMH testing per BSH.
Interpretation bands for the Anti-D Dosage. Apply clinical judgement and local guidance.
References
- RCOG Green-top Guideline No. 22: The Use of Anti-D Immunoglobulin for Rhesus D Prophylaxis. 2011.
Related
Curated clinical cross-links plus same-class fallbacks.
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Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.