McMahon Score for Acute Kidney Injury from Rhabdomyolysis
Predicts risk of acute kidney injury requiring RRT in rhabdomyolysis. Score ≥6 = high risk, warrants aggressive IV fluid therapy.
Score interpretation
McMahon < 6 — lower risk of renal replacement therapy or in-hospital death (score < 5: about 3 %).
→ Standard IV fluids; monitor renal function and urine output; CK trend daily; analgesia; treat underlying cause
McMahon ≥ 6 — high risk of renal replacement therapy or in-hospital death (score > 10: about 60 %).
→ Aggressive IV fluid resuscitation (1–2 L/h initially to urine output >200 mL/h); nephrology review; consider IV bicarbonate; HDU monitoring; early RRT preparation
Interpretation bands for the McMahon Score. Apply clinical judgement and local guidance.
References
- McMahon GM et al. A risk prediction score for kidney failure or mortality in rhabdomyolysis. JAMA Intern Med. 2013;173(19):1821–1828.
Related
Curated clinical cross-links plus same-class fallbacks.
- Glyceryl Trinitrate (Sublingual / IV) · Nitrate / Acute Angina
- Dobutamine (Acute HF / Stress Echo) · Inotrope / Acute Heart Failure
- Milrinone · Inodilator / Acute Heart Failure
- Prednisolone (Systemic) · Systemic Corticosteroid — Acute Dermatoses
- Methoxyflurane · Inhaled Analgesic — Acute Pain
- Colchicine (Acute Gout) · Anti-Inflammatory (Microtubule Inhibitor)
- Hyperkalaemia Management · UK Kidney Association Guidelines 2020; NICE CKD Guidelines
- Rhabdomyolysis · Renal Association 2018; UpToDate 2024
- Hypocalcaemia (Adult) · Society for Endocrinology
- SIADH (Endocrine Perspective) · European Hyponatraemia Guidelines 2014
- Hepatorenal Syndrome · EASL 2018; ICA 2015
- Acute Kidney Injury (AKI) · KDIGO 2012 / NICE AKI 2019
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.
