Indications for Renal Replacement Therapy (RRT) in AKI
Identifies absolute and relative indications for initiating RRT (dialysis) in acute kidney injury. Uses AEIOU mnemonic.
Score interpretation
No emergent indications. Consider relative criteria (rising urea, oliguria despite optimisation).
→ Optimise fluid status, treat reversible causes. Monitor AKI parameters. Nephrology review if AKI stage 2–3 persists.
One or more absolute RRT indications present.
→ Initiate RRT urgently. Nephrology/ICU team. Choose modality based on haemodynamic status (CRRT if unstable; IHD if stable). Vascular access (CVC). Anticoagulation protocol.
Interpretation bands for the RRT Indications. Apply clinical judgement and local guidance.
References
- KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int Suppl. 2012;2(1):1-138.
- Bellomo R et al. Acute renal failure — definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004;8(4):R204-12.
Related
Curated clinical cross-links plus same-class fallbacks.
- Estradiol (HRT — Hormone Replacement Therapy) · Oestrogen Replacement Therapy
- Nicotine · Nicotine replacement therapy (NRT)
- Pancreatin (Pancreatic Enzyme Replacement Therapy — PERT) · Pancreatic Enzyme Supplement
- Estradiol (HRT) · Oestrogen (Hormone Replacement Therapy)
- Alglucosidase Alfa · Enzyme Replacement Therapy (Lysosomal Storage Disorder)
- Asfotase Alfa · Enzyme Replacement Therapy (Hypophosphatasia — Tissue Non-specific Alkaline Phosphatase)
- Hyperkalaemia Management · UK Kidney Association Guidelines 2020; NICE CKD Guidelines
- Rhabdomyolysis · Renal Association 2018; UpToDate 2024
- Hypocalcaemia (Adult) · Society for Endocrinology
- SIADH (Endocrine Perspective) · European Hyponatraemia Guidelines 2014
- Hepatorenal Syndrome · EASL 2018; ICA 2015
- Acute Kidney Injury (AKI) · KDIGO 2012 / NICE AKI 2019
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.