Murray Score for Acute Lung Injury
Lung Injury Score (LIS) assesses severity of acute lung injury (ALI). Score ≥2.5 indicates severe ALI / ARDS. Used historically to assess ECMO candidacy.
Score interpretation
Score 0 — no lung injury
→ No specific intervention required for ALI; treat underlying cause
Score 0.1–2.4 — mild to moderate acute lung injury
→ Lung-protective ventilation; treat underlying cause; monitor closely
Score ≥2.5 — severe acute lung injury / ARDS
→ Strict lung-protective ventilation (TV 4–6 mL/kg IBW); prone positioning ≥16h/day; consider ECMO referral if P/F <80 despite optimal ventilation
Interpretation bands for the Murray Score. Apply clinical judgement and local guidance.
References
- Murray JF et al. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis. 1988;138(3):720–723.
Related
Curated clinical cross-links plus same-class fallbacks.
- Dobutamine (Acute HF / Stress Echo) · Inotrope / Acute Heart Failure
- Milrinone · Inodilator / Acute Heart Failure
- Poractant Alfa (Porcine Surfactant) · Lung Surfactant (Respiratory Distress Syndrome — Neonatal)
- Mannitol (Osmotic Diuretic — Renal/Neurological) · Acute Oliguric Renal Failure / Raised ICP
- Dexamethasone (ICU / ARDS) · Systemic Corticosteroid
- Doxapram hydrochloride · Respiratory stimulant
- Acute Asthma in Adults · BTS/SIGN British Guideline on Asthma 2019; NICE NG80
- Pulmonary Embolism Assessment · NICE NG158; ESC 2019 PE Guidelines
- Acute Exacerbation of COPD (AECOPD) · NICE NG115; GOLD 2024
- Spontaneous Pneumothorax (Adult) · BTS Pleural Disease 2023
- Atypical Pneumonia (Legionella / Mycoplasma / Chlamydophila) · BTS 2023; IDSA
- COPD Exacerbation Management · NICE NG115 / GOLD 2024
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.