Murray Score for Acute Lung Injury
Lung Injury Score (LIS) assesses severity of acute lung injury (ALI). Score above 2.5 indicates severe lung injury (ARDS). Used historically to assess ECMO candidacy.
Score interpretation
Score 0 — no lung injury
→ No specific intervention required for ALI; treat underlying cause
Score 0.1–2.5 — mild to moderate acute lung injury
→ Lung-protective ventilation; treat underlying cause; monitor closely
Score above 2.5 — severe acute lung injury / ARDS
→ Strict lung-protective ventilation (TV 4–6 mL/kg IBW); prone positioning ≥16h/day; consider ECMO referral if P/F <80 despite optimal ventilation
Interpretation bands for the Murray Score. Apply clinical judgement and local guidance.
References
- Murray JF et al. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis. 1988;138(3):720–723.
Related
Curated clinical cross-links plus same-class fallbacks.
- Dobutamine (Acute HF / Stress Echo) · Inotrope / Acute Heart Failure
- Milrinone · Inodilator / Acute Heart Failure
- Poractant Alfa (Porcine Surfactant) · Lung Surfactant (Respiratory Distress Syndrome — Neonatal)
- Mannitol (Osmotic Diuretic — Renal/Neurological) · Acute Oliguric Renal Failure / Raised ICP
- Dexamethasone (ICU / ARDS) · Systemic Corticosteroid
- Doxapram hydrochloride · Respiratory stimulant
- Acute Asthma in Adults · BTS/SIGN British Guideline on Asthma 2019; NICE NG80
- Pulmonary Embolism Assessment · NICE NG158; ESC 2019 PE Guidelines
- Acute Exacerbation of COPD (AECOPD) · NICE NG115; GOLD 2024
- Spontaneous Pneumothorax (Adult) · BTS Pleural Disease 2023
- Atypical Pneumonia (Legionella / Mycoplasma / Chlamydophila) · BTS 2023; IDSA
- COPD Exacerbation Management · NICE NG115 / GOLD 2024
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.