vascular cardiology

Dutch Lipid Clinic Network Criteria for Familial Hypercholesterolaemia (FH)

Validated scoring system for diagnosing familial hypercholesterolaemia (FH) based on family history, personal history, physical examination, LDL-cholesterol levels, and DNA analysis. Score ≥8 = definite FH. NICE and EAS recommended.

Family history*

Personal history of premature atherosclerotic disease*

Physical examination findings*

Untreated LDL-cholesterol level (mmol/L) — use pre-treatment value or calculate back-transformed value*

DNA analysis*

References

Nordestgaard BG et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease. Eur Heart J. 2013;34(45):3478–3490.
NICE CG71. Identification and management of familial hypercholesterolaemia. 2008 (updated 2017).

Curated clinical cross-links plus same-class fallbacks.

Calculators

Drugs

Pathways

Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.

References

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