Ankle-Brachial Index (ABI)
Diagnoses and grades severity of peripheral arterial disease (PAD). ABI = ankle systolic BP / brachial systolic BP. Predicts cardiovascular risk.
Score interpretation
ABI 1.00–1.40 is normal (AHA 2012).
→ PAD unlikely at rest. With exertional leg symptoms: post-exercise ABI (ACC/AHA 2016). In diabetes a normal ABI does not exclude PAD — toe pressure / toe-brachial index (NICE CG147).
ABI 0.91–0.99 is borderline (AHA 2012).
→ Cardiovascular risk-factor management; post-exercise ABI if exertional symptoms; repeat if symptoms progress.
ABI ≤ 0.90 is diagnostic of PAD (AHA 2012).
→ Secondary prevention (antiplatelet, statin, BP control, smoking cessation); supervised exercise programme for claudication (NICE CG147); vascular referral if lifestyle-limiting or the diagnosis is in doubt.
ABI < 0.5 indicates severe arterial disease (ESVS 2015).
→ Urgent vascular referral; look for rest pain or tissue loss; compression bandaging or hosiery is contraindicated.
Calcified arteries: the ABI is unreliable (AHA 2012).
→ Toe-brachial index (abnormal ≤ 0.70), toe pressure or duplex to assess for PAD.
Ischaemic rest pain, ulceration or gangrene suggests chronic limb-threatening ischaemia whatever the ABI — calcified arteries can give a normal or high ABI (Global Vascular Guidelines 2019).
→ Urgent vascular surgery referral; toe pressure / TcPO2 and duplex; WIfI staging; wound care.
Interpretation bands for the Ankle-Brachial Index. Apply clinical judgement and local guidance.
References
Related
Curated clinical cross-links plus same-class fallbacks.
- Naftidrofuryl Oxalate · 5-HT2 Receptor Antagonist — Peripheral Arterial Disease (Intermittent Claudication)
- Alteplase (Peripheral Arterial / DVT Use) · Thrombolytic — Catheter-Directed Thrombolysis / Peripheral Arterial Occlusion
- Amlodipine · Dihydropyridine Calcium Channel Blocker — Raynaud's / Peripheral Vascular Disease / Hypertension
- Streptokinase · Thrombolytic — Peripheral Arterial Occlusion / DVT (Historical)
- Selexipag · Pulmonary Arterial Hypertension
- Macitentan · Pulmonary Arterial Hypertension
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.