Urinary Tract Infection

Also: UTI · cystitis · pyelonephritis

Urinary tract infections (UTIs) range from simple cystitis to pyelonephritis and urosepsis. Care depends on the site and severity, the patient group, and local resistance patterns guiding antibiotic choice.

Relevant scores, antibiotics and pathways are gathered here.

Decision pathways

Urinary Tract Infection in Children

NICE CG54 2007 (updated 2022)
UTI Management

NICE NG109 2018
Recurrent UTI in Women

NICE NG112 / CKS; EAU 2024
Acute Pyelonephritis

NICE; BAUS; RCOG — CG109, NG109
UTI in Men

NICE NG109; BAUS
Urethral Stricture

BAUS

Drugs

Co-amoxiclav (Amoxicillin/Clavulanate)

Beta-lactam + beta-lactamase inhibitor
Amoxicillin (Otitis Media / Sinusitis)

Beta-lactam antibiotic
Co-amoxiclav 625mg (Augmentin)

Beta-lactam + beta-lactamase inhibitor antibiotic
Co-Amoxiclav

Antibiotic (Penicillin + Beta-Lactamase Inhibitor)
Amoxicillin

Antibiotic (Penicillin)
Trimethoprim

Antibiotic (Folate Synthesis Inhibitor)
Nitrofurantoin

Antibiotic (Nitrofuran)
Co-trimoxazole (Trimethoprim + Sulfamethoxazole)

Sulphonamide + Folate Synthesis Inhibitor Combination
Nitrofurantoin (UTI Treatment)

Urinary Antiseptic
Cefalexin

First-Generation Cephalosporin — Skin / Soft Tissue / UTI
Fosfomycin

Phosphonic Acid Antibiotic — Uncomplicated UTI / ESBL / MDR Gram-Negatives
Pivmecillinam hydrochloride

Penicillin (amidinopenicillin)

Decision support only. These tools are aggregated by topic to aid navigation — always apply clinical judgement and the relevant national or local guideline.