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Mild–moderate topical corticosteroid

Alclometasone dipropionate

Brand names: Modrasone

Alclometasone dipropionate is a mild-to-moderate potency topical corticosteroid used for inflammatory and pruritic dermatoses such as eczema.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

It acts on glucocorticoid receptors in the skin to exert anti-inflammatory, vasoconstrictive and immunosuppressive effects, reducing redness, swelling and itch.

Prescribing in practice

  • Apply thinly to affected areas for the shortest effective period to limit local effects such as skin thinning and systemic absorption, especially on the face, flexures and in children.
  • Avoid use on untreated infected skin unless an appropriate antimicrobial is also given, as corticosteroids can mask or worsen infection.
  • Prolonged or extensive use under occlusion increases systemic absorption and the risk of adrenal suppression.

Monitoring

Monitor the treated skin for response and for signs of atrophy or infection with prolonged use.

Counselling the patient

  • Apply a thin layer only to the affected areas as directed.
  • Do not use continuously on the face or skin folds for long periods without review.
  • Report worsening, spreading or signs of skin infection.

Evidence & guidelines

Topical corticosteroids are a mainstay of eczema management, with potency and duration guided by current prescribing references.

Reference: NICE CKS Eczema – atopic; BAD topical steroid guidance; SmPC Modrasone; Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.

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