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Oral rehydration salts

Potassium chloride with rice powder, sodium chloride and sodium citrate

Brand names: Dioralyte Relief

Used in: Hyponatraemia

This is an oral rehydration salts preparation containing potassium chloride, rice powder, sodium chloride and sodium citrate, used to treat and prevent dehydration from acute diarrhoea.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

Glucose or rice-derived carbohydrate drives co-transport of sodium and water across the intestinal mucosa, while the salts replace electrolyte losses and citrate corrects the acidosis of diarrhoeal illness.

Prescribing in practice

  • Reconstitute only with the recommended volume of clean water and never add extra salt or sugar, as incorrect concentration can cause hypernatraemia, particularly in infants.
  • It is not a substitute for intravenous fluids in severe dehydration, shock or persistent vomiting, where parenteral resuscitation is required.
  • The potassium content warrants caution in renal impairment or where potassium excretion is reduced.

Monitoring

Monitor hydration status, urine output and, where dehydration is significant, serum electrolytes during rehydration.

Counselling the patient

  • Make up the solution exactly as directed with clean water and discard any unused reconstituted solution after the stated time.
  • Continue normal feeding and breastfeeding, and seek medical help if dehydration worsens or the person cannot keep fluids down.

Evidence & guidelines

Oral rehydration therapy is endorsed by the WHO as the mainstay of management for acute diarrhoeal dehydration, with rice-based formulations offering an alternative carbohydrate source.

Reference: NICE CG84; WHO; Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.