Emergency Medicine Drugs

127 drugs

Quick-reference dosing for 127 emergency medicine medicines, aligned to current UK formularies. Each entry lists adult, paediatric and (where relevant) neonatal doses, renal and hepatic adjustments, contraindications, key interactions, monitoring and clinical pearls — with the source reference. Always confirm doses against current prescribing references before prescribing.

Acetylcysteine (N-acetylcysteine — NAC)

Antidote — paracetamol overdose / Hepatoprotectant
Activated charcoal

Adsorbent (gut decontamination)
Activated Charcoal

Gastrointestinal decontamination / Antidote
Adenosine

Antiarrhythmic
Adrenaline (Anaphylaxis Protocol)

Auto-injector / IM adrenaline for anaphylaxis
Adrenaline (epinephrine)

Sympathomimetic (alpha + beta agonist)
Adrenaline (Epinephrine)

Vasopressor
Alteplase (tPA)

Thrombolytic — Ischaemic Stroke / Massive PE
Aminophylline IV

Xanthine bronchodilator (theophylline ethylenediamine)
Amiodarone

Antiarrhythmic
Andexanet Alfa (Ondexxya)

Factor Xa inhibitor reversal agent
Angiotensin II (Human)

Vasopressor (Angiotensin II Receptor Agonist)
Aspirin (Loading Dose)

Antiplatelet — ACS / Ischaemic Stroke
Atropine

Anticholinergic
Benzylpenicillin (Penicillin G)

Beta-lactam antibiotic (natural penicillin)
Bivalirudin

Anticoagulation
Calcium chloride

IV calcium salt (high elemental calcium)
Calcium Gluconate 10%

Electrolyte
Ceftriaxone

Third-generation cephalosporin
Cetirizine hydrochloride

Non-sedating H1 antihistamine
Chlorphenamine maleate

Sedating H1 antihistamine
Clopidogrel (Loading Dose)

P2Y12 Inhibitor Antiplatelet — ACS
Codeine phosphate

Weak opioid analgesic
Conestat alfa

Recombinant C1 esterase inhibitor
Cyproheptadine

Antidote / Antihistamine
Desferrioxamine Mesilate (Deferoxamine)

Antidote / Chelating Agent
Desmopressin

Haemostasis
Dextrose 10% IV

IV glucose solution (hypoglycaemia treatment)
Dextrose 50% (Glucose 50%)

Glucose Supplement
Dicobalt edetate

Cyanide antidote (chelator)
Digoxin-specific antibody fragments

Digoxin antidote (Fab fragments)
Digoxin-specific Antibody Fragments (DigiFab)

Antidote
Dimercaprol

Antidotes & Toxicology
Dobutamine

Positive inotrope (beta-1 agonist)
Dopamine

Catecholamine vasopressor / inotrope (dose-dependent)
Esmolol

Ultra-short-acting selective beta-1 blocker
European viper snake venom antiserum

Antivenom
Fentanyl

Analgesic
Fexofenadine hydrochloride

Non-sedating H1 antihistamine
Flumazenil

Benzodiazepine Antagonist
Folinic Acid (Calcium Folinate / Leucovorin)

Antidote / Chemotherapy Support
Fomepizole

Antidotes & Toxicology
Garadacimab

Anti-factor XIIa monoclonal antibody
Gelatin (succinylated)

Colloid plasma volume expander
Glucagon

Endogenous peptide hormone / antidote
Glucarpidase

Recombinant carboxypeptidase G2
Glucose

Carbohydrate / hypoglycaemia treatment
Glyceryl Trinitrate (GTN)

Nitrate (vasodilator)
Grass pollen extracts

Allergen immunotherapy
House dust mite extracts

Allergen immunotherapy
Hydrocortisone

Corticosteroid
Hydroxocobalamin (Cyanokit)

Cyanide antidote
Icatibant

Bradykinin B2 receptor antagonist
Idarucizumab (Praxbind)

Dabigatran reversal agent (specific antidote)
Ketamine

Anaesthetic
Ketorolac trometamol

Non-selective NSAID
L-Carnitine

Antidote / Metabolic Agent
Labetalol (IV — Hypertensive Emergency)

Combined alpha and beta blocker
Lanadelumab

Anti-plasma kallikrein monoclonal antibody
Levetiracetam (IV)

Antiepileptic — Status Epilepticus (Second-Line)
Levocetirizine hydrochloride

Non-sedating H1 antihistamine
Lidocaine with adrenaline

Local anaesthetic + vasoconstrictor
Lidocaine with cetrimide

Local anaesthetic + antiseptic
Lidocaine with phenylephrine

Local anaesthetic + vasoconstrictor
Lipid Emulsion 20% (Intralipid)

Antidote / Resuscitation
Loratadine

Non-sedating H1 antihistamine
Lorazepam

Benzodiazepine
Magnesium sulfate

Electrolyte / antiarrhythmic / anticonvulsant
Magnesium Sulphate

Electrolyte
Magnesium Sulphate IV (Additional Indications)

Magnesium salt / bronchodilator / antiarrhythmic
Mannitol

Osmotic diuretic
Meptazinol

Mixed agonist-antagonist opioid
Methoxyflurane

Inhaled Analgesic — Acute Pain
Methylene Blue

Antidotes & Toxicology
Methylprednisolone

Corticosteroid — IV
Methylthioninium chloride (methylene blue)

Antidote / dye
Midazolam

Benzodiazepine
Mizolastine

Non-sedating H1 antihistamine
Morphine

Analgesic
Naloxone

Opioid Antagonist
Naloxone hydrochloride

Pure μ-opioid receptor antagonist
Noradrenaline (norepinephrine)

α/β adrenergic agonist (predominantly α1)
Noradrenaline (Norepinephrine)

Vasopressor
Octreotide

Gastrointestinal Emergency
Oxycodone hydrochloride

Strong opioid
Oxycodone with naloxone

Strong opioid + peripheral opioid antagonist
Paracetamol with buclizine and codeine

Combined analgesic + antihistamine + opioid
Paracetamol with isometheptene

Combined analgesic + sympathomimetic
Pethidine hydrochloride

Strong opioid (synthetic phenylpiperidine)
Phentolamine

Non-selective alpha-adrenoceptor antagonist
Phenylephrine hydrochloride

α1-adrenoceptor agonist (vasopressor)
Phenytoin / Fosphenytoin

Antiepileptic — Status Epilepticus (Second-Line)
Potassium chloride with calcium chloride and sodium chloride

Crystalloid IV fluid
Potassium chloride with calcium chloride sodium chloride and sodium lactate

Balanced crystalloid IV fluid
Potassium chloride with glucose

IV fluid (potassium + dextrose)
Potassium chloride with glucose and sodium chloride

IV fluid (mixed)
Potassium chloride with rice powder, sodium chloride and sodium citrate

Oral rehydration salts
Potassium chloride with sodium chloride

IV fluid (potassium + saline)
Pralidoxime

Antidotes & Toxicology
Pralidoxime chloride

Cholinesterase reactivator (oxime)
Prilocaine hydrochloride

Amide local anaesthetic
Prilocaine with felypressin

Amide LA + vasopressin analogue
Promethazine hydrochloride

First-generation H1-antihistamine (phenothiazine)
Promethazine teoclate

H1-antihistamine (theoclate salt)
Protamine sulfate

Heparin antagonist
Prothrombin Complex Concentrate (PCC)

Coagulation Factor Concentrate — Warfarin Reversal
Pyridoxine (Vitamin B6)

Antidote / Vitamin
Rocuronium

Neuromuscular Blocker
Sodium Bicarbonate 8.4%

Electrolyte Buffer
Sodium bicarbonate with sodium chloride

Alkalinising IV solution
Sodium chloride

Saline IV fluid / replacement
Sodium chloride with glucose

IV fluid (saline + dextrose)
Sodium Nitrite

Antidotes & Toxicology
Sodium Thiosulfate

Antidotes & Toxicology
Suxamethonium (Succinylcholine)

Neuromuscular Blocker
Tenecteplase

Cardiovascular Emergency
Terlipressin

Gastrointestinal Emergency
Tetracaine

Topical ester local anaesthetic
Thiamine (IV/IM — Pabrinex)

Vitamin B1 (Thiamine) — deficiency treatment / Wernicke's encephalopathy prevention
Tirofiban

Cardiovascular Emergency
Tolfenamic acid

NSAID (anthranilic acid)
Tramadol hydrochloride

Atypical opioid (μ-agonist + SNRI)
Tramadol with dexketoprofen

Opioid + NSAID combination
Tramadol with paracetamol

Opioid + paracetamol combination
Tranexamic Acid (TXA)

Antifibrinolytic
Unfractionated Heparin (IV)

Anticoagulant — ACS / PE / Thrombus
Vasopressin / Terlipressin

Vasopressin Analogue — Vasodilatory Shock / Variceal Bleeding