Synthetic cannabinoid
Nabilone
Brand names: Cesamet
Adult dose
Dose: 1mg PO BD; max 2mg TDS
Route: PO
Frequency: BD-TDS
Clinical pearls
- Chemotherapy-induced nausea/vomiting unresponsive to standard antiemetics
- CD2 controlled drug; specialist initiation; warn about driving
Contraindications
- Severe psychiatric history
- Severe hepatic impairment
- Pregnancy/breastfeeding
- Hypersensitivity
Side effects
- Drowsiness
- Dizziness
- Dry mouth
- Euphoria/dysphoria
- Hallucinations
- Tachycardia
- Hypotension
Interactions
- CNS depressants
- Anticholinergics
- Sympathomimetics
- Alcohol
Monitoring
- Sedation
- Mental state
- BP
Reference: BNF; NICE TA313; https://bnf.nice.org.uk/drugs/nabilone/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Pathways
- Acute Myeloid Leukaemia Presentation · BSH; NICE — NG146
- Tumour Lysis Syndrome · Cairo-Bishop; BSH; NICE — Best Practice
- Lower Gastrointestinal Bleed · BSG 2019; NICE NG141
- Variceal Upper GI Bleed · BSG 2015; Baveno VII (2022)
- Spontaneous Bacterial Peritonitis (SBP) · BSG / EASL 2018
- Hepatorenal Syndrome · EASL 2018; ICA 2015