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Antifoaming agent

Simeticone

Brand names: Infacol, Wind-eze

Simeticone is an antifoaming agent used to relieve flatulence, bloating, and trapped wind, and to reduce gas prior to some abdominal imaging or endoscopy.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

It lowers the surface tension of gas bubbles in the gut, causing them to coalesce and be passed more easily, without being absorbed systemically.

Prescribing in practice

  • It is pharmacologically inert and not absorbed, giving it a very favourable safety profile and making it suitable across a wide range of patients.
  • It provides only symptomatic relief and does not address an underlying cause of persistent or alarm symptoms.
  • It is also a component of some combined antacid and infant colic preparations.

Monitoring

No laboratory monitoring is required; assess symptomatic benefit clinically.

Counselling the patient

  • Take it after meals and at bedtime for trapped wind if symptoms persist.
  • Seek review if abdominal symptoms continue or worsen despite treatment.

Evidence & guidelines

Simeticone is a long-established over-the-counter remedy for gas-related abdominal symptoms.

Reference: NICE CKS; Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.

Pathways