Antifoaming agent Pregnancy: §4.6: as dimeticone is not absorbed, no adverse effects on pregnancy and lactation are anticipated; however, as with all drugs, caution should be exercised in these conditions. (Source SPC uses the term 'dimeticone' in this section.)

Simeticone

Brand names: Infacol, Wind-eze

Simeticone is an antifoaming agent used to relieve flatulence, bloating, and trapped wind, and to reduce gas prior to some abdominal imaging or endoscopy.

Auto-extracted from the source labelling — not yet independently clinician-verified. These values were distilled from the UK SPC (or the US label where noted) but have not had a clinician sign-off. Confirm against the current SmPC before prescribing.

Adult dose

Dose: One or two capsules

Route: Oral

Frequency: 3 or 4 times daily, or as required for relief

eMC §4.2 (WindSetlers, UK SPC). The SPC states this single regimen for 'Adults, the elderly and children' without differentiating by age or weight - no per-kg or age-banded paediatric dose is given, so verify any under-18 use against a children's formulary. No maximum daily dose and no capsule strength were stated in the fetched sections - clinician to confirm the product strength from the full SPC. §4.4 special warnings: 'None stated.'

Dose auto-extracted from UK Summary of Product Characteristics (SPC) via the eMC — not yet clinician-verified. Always confirm against the product SmPC and your local formulary before prescribing.

Contraindications

Hypersensitivity to any of the ingredients (§4.3)

Side effects

Nausea (minor adverse effect)
Constipation (minor adverse effect)
Rare hypersensitivity reactions: rash
Rare hypersensitivity reactions: pruritis, facial oedema, tongue oedema
Rare hypersensitivity reactions: respiratory difficulty

Interactions

§4.5: 'None reported.'

Clinical monograph

How it works

It lowers the surface tension of gas bubbles in the gut, causing them to coalesce and be passed more easily, without being absorbed systemically.

Prescribing in practice

It is pharmacologically inert and not absorbed, giving it a very favourable safety profile and making it suitable across a wide range of patients.
It provides only symptomatic relief and does not address an underlying cause of persistent or alarm symptoms.
It is also a component of some combined antacid and infant colic preparations.

Monitoring

No laboratory monitoring is required; assess symptomatic benefit clinically.

Counselling the patient

Take it after meals and at bedtime for trapped wind if symptoms persist.
Seek review if abdominal symptoms continue or worsen despite treatment.

Evidence & guidelines

Simeticone is a long-established over-the-counter remedy for gas-related abdominal symptoms.

Reference: NICE CKS; Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. The structured dose values shown have been reviewed by a clinician. Monograph status: clinician-reviewed (2026-07-04).

Curated clinical cross-links plus same-class fallbacks.

Pathways