Fusidic acid

The strength is pinned by the product itself — the source product is 'Fucidin 20 mg/g Cream' — so the application instruction is publishable even though no gram quantity per application is stated; SPCs do not quantify topical application amounts. FULL §4.2 VERBATIM: 'Posology Adults and Paediatric population Uncovered lesions - apply gently three or four times daily. Covered lesions - less frequent applications may be adequate. Method of administration Cutaneous use.' NO MAXIMUM is stated — §4.2 contains no 'maximum' or 'up to' ceiling cue, so maxDose is left empty; four times daily is simply the upper end of the stated frequency range, not a declared ceiling. NO DURATION is stated in the fetched §4.2. What the SPC does say about duration is a resistance warning, not a dose limit (§4.4 verbatim): 'Bacterial resistance among staphylococcus aureus has been reported to occur with the use of topical Fucidin. As with all antibiotics, extended or recurrent use may increase the risk of developing antibiotic resistance. Extended or recurrent use may increase the risk of developing contact sensitisation.' EXCIPIENT CAUTIONS (§4.4 verbatim): 'Fucidin cream contains butylhydroxyanisole, cetyl alcohol and potassium sorbate. These excipients may cause local skin reactions (e.g. contact dermatitis). Butylhydroxyanisole may also cause irritation to the eyes and mucous membranes. Fucidin cream should therefore be used with care when applied in the proximity of the eyes. Fucidin cream contains polysorbate 60. Polysorbates can cause allergic reactions.' FIRE HAZARD (§4.4 verbatim): 'Instruct patients not to smoke or go near naked flames – risk of severe burns. Fabric (clothing, bedding, dressings etc) that has been in contact with this product burns more easily and is a serious fire hazard. Washing clothing and bedding may reduce product build-up but not totally remove it.' INTERACTIONS (§4.5 verbatim): 'No interaction studies have been performed. Interactions with systemically administered medicinal products are considered minimal as the systemic absorption of topical Fucidin is negligible.' — note this means the statin/rhabdomyolysis interaction the page lists is a SYSTEMIC fusidate issue and is not addressed by this topical SPC.

dosePerKg is null because this SPC gives children the SAME topical application regimen as adults and states no weight-based figure anywhere — a topical cream has no per-kilogram dose, so no weight calculator is offered. VERBATIM §4.2 heading and text: 'Posology Adults and Paediatric population Uncovered lesions - apply gently three or four times daily. Covered lesions - less frequent applications may be adequate.' Paediatric safety (§4.8 verbatim): 'Frequency, type and severity of adverse reactions in children are expected to be the same as in adults.' No minimum age, no neonatal statement and no paediatric duration limit appear anywhere in the fetched SPC — verify against a children's formulary before use in young children.